Studies on the effects of CBD on liver function have produced mixed results. In clinical trials for the FDA-approved CBD-based drug Epidiolex, between 5 and 20 percent of patients experienced increased levels of liver enzymes. In a separate study on laboratory mice, those treated with higher concentrations of CBD died or were close to death within 24 hours of ingestion. Unfortunately, there is not enough information available on the long-term effects of CBD on humans, let alone dogs.
In experimental models, CBD has been found to effectively reduce inflammation, oxidative stress, and promote the death of malignant cells in the liver. Full Spectrum Hemp Extract (CBD) has been shown to reduce the duration and frequency of seizures, reduce inflammation and pain associated with arthritis and pancreatitis, decrease allergy symptoms, help with anxiety, maintain optimal blood sugar levels in people with diabetes, relieve symptoms of Cushing's Disease and other autoimmune diseases, and even shrink tumors (including skin tumors). Studies have demonstrated that CBD is safer for dogs than many commonly prescribed drugs. As a result, the FDA has cracked down on products containing CBD that make claims or statements about what the ingredient can do.
Even though some CBD products contain trace amounts of THC, these amounts are insignificant compared to the amount needed to feel high. Doses as high as 20 mg of CBD per kg pose no threat to liver health, as proven in the clinical trial of Epidiolex, a CBD-based anticonvulsant medication. Smaller doses of CBD, equivalent to 50 milligrams for a human, caused swelling and liver damage in mice. Due to the prevalence of liver damage associated with CBD use, many people in the United States are turning to alternative methods for consuming it.
Many CBD users agree that taking a tincture is one of the simplest ways to ingest CBD oil because of its convenient packaging. To avoid any potential interactions between CBD and medications and minimize liver stress, people with liver disorders should limit their use of over-the-counter (OTC) medications. Learn more about some of the best CBD pills and capsules on the market and how to choose a quality product. While this isn't dangerous, it can lead some CBD users to look for different ways to consume it.